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MilliporeSigma™ Calbiochem™ TACE Substrate IV, Fluorogenic

Catalog No. 6164071MG Shop All MilliporeSigma Products
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61-640-71MG 1 mg
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Description

An internally-quenched fluorogenic decapeptide substrate that is useful for continuous monitoring of TACE activity and high-throughput screening of TACE inhibitors (kcat =

An internally-quenched fluorogenic decapeptide substrate that is useful for continuous monitoring of TACE activity and high-throughput screening of TACE inhibitors (kcat = 21.6 s-1 and substrate concentration at half the Vmax, S0.5 = 342μM). The substrate is cleaved at Ala-Val amide bond. Acts as a poor substrate for MMP-1, MMP-9, and MMP-13. Displays better solubility in aqueous buffers.
TRUSTED_SUSTAINABILITY

Specifications

Color Yellow
Formulation Supplied as a trifluoroacetate salt.
Description 95% by HPLC
Target Proteins Fluorogenic decapeptide substrate that is useful for continuous monitoring of TACE activity
Molecular Formula C59H93N23O20
Formula Weight 1444.5g/mol
Solubility DMSO
Content And Storage Protect from Light, Protect from Moisture
Form Lyophilized
Quantity 1 mg
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