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MilliporeSigma™ Calbiochem™ V-ATPase Inhibitor, KM91104
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Quantity:
10 mg
Description
A cell-permeable, non-macrolide small molecule V-ATPase inhibitor that specifically targets the a3-b2 subunit protein protein interation of V-ATPase (IC50 of 2.3μM), in vitro . It is also shown to inhibit osteoclast resorption (IC50 of 1.2μM) on both synthetic hydroxyapatite surfaces and dentin slices in an in vitro osteoclast model, RANKL-differentiated RAW 264.7 cells, without significantly affecting RAW 264.7 cell viability or RANKL-mediated osteoclast differentiation.

Specifications
Specifications
Color | Off-white |
Description | >95% by HPLC |
Molecular Formula | C14H12N2O4 |
Formula Weight | 272.08g/mol |
Solubility | DMSO |
Content And Storage | Protect from light |
Form | Solid |
Quantity | 10 mg |
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