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MilliporeSigma™ Calbiochem™ Vigabatrin

Catalog No. 5059890001 Shop All MilliporeSigma Products
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10mg

A selective, irreversible inhibitor of GABA transaminase with antiepileptic properties

A selective, irreversible inhibitor of GABA transaminase with antiepileptic properties. Covalently binds to the active site of GABA tansaminase to inactivate it in a dose-dependent manner and increases extracellular GABA levels in the brain. Rapidly absorbed following oral administration and is shown to inhibit [3H]GABA uptake across the apical membrane of Caco-2 cell monolayers in a concentration-dependent manner (IC50 = 2.9 mM)
TRUSTED_SUSTAINABILITY

Specifications

Color White
Description 99% by HPLC
Target Proteins GABA Transaminase
Molecular Formula C6H11NO2
Solubility H2O
Content And Storage Protect from light
Form Solid
Quantity 10 mg
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