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MilliporeSigma™ Calbiochem™ Zinc (II) Protoporphyrin IX

Catalog No. 69155025MG Shop All MilliporeSigma Products
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69-155-025MG 25 mg
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Description

A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin.

A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin. Inhibits soluble guanylyl cyclase and produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50 = 800 nM, 4μM, and 5μM for nNOS, iNOS, and eNOS, respectively). Inhibits relaxation induced by acetylcholine, ANP, and VIP in isolated rat aorta. Blocks interleukin-1 and prevents induction of long-term potentiation. Also useful as an indicator of iron-deficient erythropoiesis. Does not cross the blood-brain barrier.
TRUSTED_SUSTAINABILITY

Specifications

Color Dark Red
Description 95% by TLC
Target Proteins heme oxygenase
CAS 15442-64-5
Molecular Formula C34H32N4O4Zn
Formula Weight 626g/mol
Solubility DMF or pyridine
Content And Storage Protect from light
Form Solid
Quantity 25 mg
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