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MilliporeSigma™ Calbiochem™ Zinc (II) Protoporphyrin IX
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Quantity:
25 mg
Description
A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin. Inhibits soluble guanylyl cyclase and produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50 = 800 nM, 4μM, and 5μM for nNOS, iNOS, and eNOS, respectively). Inhibits relaxation induced by acetylcholine, ANP, and VIP in isolated rat aorta. Blocks interleukin-1 and prevents induction of long-term potentiation. Also useful as an indicator of iron-deficient erythropoiesis. Does not cross the blood-brain barrier.

Specifications
Specifications
Color | Dark Red |
Description | 95% by TLC |
Target Proteins | heme oxygenase |
CAS | 15442-64-5 |
Molecular Formula | C34H32N4O4Zn |
Formula Weight | 626g/mol |
Solubility | DMF or pyridine |
Content And Storage | Protect from light |
Form | Solid |
Quantity | 25 mg |
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