Calciferol, 97%, Thermo Scientific Chemicals

Description

Calciferol has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Calciferol has also been shown to be an inhibitor of DNA polymerase. Calciferol with calcium is used to treat or prevent bone loss (osteoporosis). Calciferol is also used with other medications to treat low levels of calcium or phosphate caused by certain disorders (such as hypoparathyroidism, pseudohypoparathyroidism, familial hypophosphatemia). It is often used in kidney disease to keep calcium levels normal and allow normal bone growth.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in ethanol (80 mg/ml at 25°C), water (<1mg/mL at 25°C), methanol, DMF (∼20 mg/ml), and DMSO (20 mg/ml at 25°C).

Notes
Store at 4°C. Incompatible with heat and oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 50-14-6
• Molecular Formula: C28H44O
• Molecular Weight (g/mol): 396.66
• MDL Number: MFCD00166988,MFCD11656674
• InChI Key: MECHNRXZTMCUDQ-VLOQVYPSSA-N
• Synonym: ergocalciferol, vitamin d2, calciferol, viosterol, oleovitamin d2, ercalciol, ergorone, detalup, condocaps, crystallina
• PubChem CID: 134129658
• IUPAC Name: (1S)-3-[2-[(1S,7aR)-1-[(2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol
• SMILES: CC(C)[C@@H](C)\C=C\[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1/C[C@@H](O)CCC1=C

• Melting Point: 118°C to 119°C
• Color: White
• Quantity: 1 g
• UN Number: UN2811
• Beilstein: 1916682
• Merck Index: 14,10018
• Solubility Information: Soluble in ethanol (80mg/ml at 25°C),water (<1mg/ml at 25°C),methanol,DMF (∽20mg/ml),and DMSO (20mg/ml at 25°C).
• Optical Rotation: +110° (c=1.5 in Ethanol)
• Formula Weight: 396.66
• Percent Purity: 97%
• Physical Form: Powder
• Chemical Name or Material: Calciferol

Safety and Handling

Hazard Category	H301+H311-H330-H372
Hazard Statement	GHS H Statement H301-H311-H330-H372 Toxic if swallowed. Toxic in contact with skin. Fatal if inhaled. Causes damage to organs through prolonged or repeated exposure.
Precautionary Statement	P260-P264b-P270-P271-P280-P284-P301+P310-P302+P352-P304+P340-P310-P312-P314-P330-P361-P363-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	200-014-9
RTECSNumber	KE1050000
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only