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Cayman Chemical CalcIum Ionphore I 25mg

Supplier: Cayman Chemical 1740725 MG

Inhibits the p53-Mdm2 interaction (Ki 83 nM) and also dose-dependently reduces activation of the NF-KB pathway prevents phosphorylation of IKBa by IKKa IKKB and IKKɛ (IC50s 80.5 78.2 and 57.1 UM respectively) inhibits the growth of A549 cell xenografts in mice
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