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Medchemexpress LLC Calmodulin Binding Peptide 1 | 104041-80-7 | 98.7% | 5301.10 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHYP1805

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Calmodulin Binding Peptide 1 is a high-affinity (pM) CaM-binding peptide derived from smooth muscle myosin light chain kinase (MLCK peptide). The interface of the complex formed by Calmodulin Binding Peptide 1 and Ca2+-CaM can be specifically bound by small-molecule inhibitors, serving as a key target for selective regulation of smooth muscle contraction and development of anti-CaM drugs.

  • High-affinity (pM) CaM-binding peptide.
  • Derived from smooth muscle myosin light chain kinase (MLCK peptide).
  • The complex with Ca2+-CaM can be specifically bound by small-molecule inhibitors.
  • Serves as a key target for selective regulation of smooth muscle contraction.
  • Used for the development of anti-CaM drugs.
  • Binds to the human calmodulin fluorescent biosensor hCaM M124C-mBBr with high affinity (Kd = 2.55 ± 1.75 pM) in vitro.
  • Can displace the lower-affinity inhibitor MBC from the biosensor.

Catalog No. 50-004-25479


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