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Medchemexpress LLC Calpain inhibitor I | 110044-82-1 | ≥98.0% | 383.53 | 25 MG
Supplier: Medchemexpress LLC 25MGHY18964
MG-101 (ALLN) is an inhibitor of cysteine proteases, specifically inhibiting calpain I, calpain II, cathepsin B, and cathepsin L with Kis of 190, 220, 150, and 500 pM, respectively. It induces apoptosis and inhibits tumor growth, and can be used for research on colon cancer.
- Inhibits calpain I, calpain II, cathepsin B, and cathepsin L.
- Induces apoptosis.
- Inhibits tumor growth.
- Affects the growth of colon cancer HCT116 cells.
- Induces Bax-dependent apoptosis in HCT116 cells.
- Useful for research on colon cancer.
- Demonstrates efficacy in inhibiting tumor growth in nude mice.
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