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Medchemexpress LLC Calpain Inhibitor III | 88191-84-8 | 97.0% | 382.45 | 50 MG
Supplier: Medchemexpress LLC HY1823650MG
MDL-28170 (Calpain Inhibitor III) is a potent, selective, and membrane-permeable cysteine protease inhibitor of calpain that rapidly penetrates the blood-brain barrier following systemic administration. MDL-28170 also blocks γ-secretase. It significantly and time-dependently improves the recovery of synaptic responses in hippocampal slices following prolonged, moderate hypoxia without hypoxic depolarization. MDL-28170 dose-dependently inhibits brain cysteine proteinase activity.
- Potent, selective and membrane-permeable cysteine protease inhibitor of calpain.
- Rapidly penetrates the blood-brain barrier following systemic administration.
- Blocks γ-secretase.
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