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Cayman Chemical CalpaIn InhIbItr XII 1mg

Supplier: Cayman Chemical 144661 MG

A MRN complex inhibitor inhibits DSB-induced H2AX phosphorylation (IC50 66 UM in X. laevis cell-free extracts) inhibits the exonuclease activity of Mre11 in a cell-free assay at 100 UM induces cell cycle arrest at the G2 phase in TOSA4 cells and inhibits homology-dependent repair in HEK293 cells in a concentration-dependent manner reduces tumor growth in an LA-N-5 mouse xenograft model when encapsulated in nanoparticles at 50 mg/kg
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