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Enzo Life Sciences Calpeptin (50mg). CAS: 117591-20-5

Supplier: Enzo Life Sciences BMLPI1010050

Membrane permeable inhibitor of calpain I and II, cathepsin L and cathepsin K (IC50=0.11 nM). Promotes neurite elongation in differentiating PC12 cells. Prevents Ca2+-ionophore induced degradation of actin binding protein and P235 in platelets. Inhibits myosin light chain phosphorylation in platelets stimulated by collagen, ionomycin (ALX-450-006) or thrombin. Inhibits LPS induced iNOS transcription and NF-κB activation, possibly via proteasome inhibition. Alternative name: Z-Leu-norleucinal, N-Benzyloxycarbonyl-L-leucyl-norleucinal. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (25mg/ml), 100% ethanol (25mg/ml or dimethyl formamide (5mg/ml). Long Term Storage: -20°C.
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