Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organopnictogen compounds
  6. Calpeptin, Tocris Bioscience™

Calpeptin, Tocris Bioscience™

Catalog No. 044810
Click to view available options
Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Calpain and cathepsin L inhibitor

Potent, cell-permeable inhibitor of the Ca2+-dependent protease, calpain. Prevents collagen- and thrombin-induced platelet aggregation, probably by blocking calpain induced phospholipase C and thromboxane synthase activation. Potent cathepsin L inhibitor. Recently shown to preferentially inhibit a subset of protein-tyrosine phosphatases. Also inhibits SARS-CoV-2 Mpro in vitro (IC50 = 10.7 μM) and inhibits viral replication.

Chemical Identifiers

CAS 117591-20-5
Molecular Formula C20H30N2O4
Molecular Weight (g/mol) 362.47
InChI Key PGGUOGKHUUUWAF-ROUUACIJSA-N
Synonym calpeptin, n-cbz-leu-nleu-al, benzylcarbonyl-leu-nleu-h, unii-18x9fr245w, chembl92708, n-benzyloxycarbonyl-l-leucylnorleucinal, carbamic acid, 1-1-formylpentyl amino carbonyl-3-methylbutyl-, phenylmethyl ester, s-r*,r*, benzyl n-1s-3-methyl-1-2s-1-oxohexan-2-yl carbamoyl butyl carbamate, carbamic acid, 1-1-formylpentyl amino carbonyl-3-methylbutyl-, phenylemthyl ester, s-r*,r*
PubChem CID 73364
ChEBI CHEBI:3330
IUPAC Name benzyl N-[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxohexan-2-yl]amino]pentan-2-yl]carbamate
SMILES CCCCC(C=O)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1

Specifications

Quantity 10 mg
Formula Weight 362.47
Percent Purity >98%
Chemical Name or Material Calpeptin

Safety and Handling

Recommended Storage Desiccate at +4°C
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.