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Enzo Life Sciences CaM kinase 2 (281-309) (0.5mg)

Supplier: Enzo Life Sciences BMLP2010500

Sequence is from Ca2+/calmodulin-dependent kinase A subunit negative regulatory sequence containing the calmodulin binding site (290-309) plus autophosphorylation site (Thr286). Peptide can be phosphorylated at Thr286 by PKC. Useful as a CaM binding peptide and inhibits CaMKII by blocking Ca2+/CaM activation and the enzyme active-site. IC50=80 nM, CaM binding; IC50=2 µM, active-site. Alternative name: CaMK2 (281-309), Ca2+ / calmodulin dependent protein kinase II (281 309). Purity: ≥97%. Long Term Storage: -20°C.
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