CAMK2G has six alternatively spliced variants that encode six different isoforms. Some of these variants have been identified in human tumors. Transgenic mice expressing a partially calcium-independent mutant form of CAMKG showed 1.5- to 2-fold increase in the thymus of these mice, at least in part due to an increase in the life span of double-positive thymocytes. There was an increase in the number of T cells in the secondary lymphoid organs that had acquired an antigen-dependent memory phenotype.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Safety and Handling
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