Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Camonsertib | 2417489-10-0 | 99.99% | 410.47 | 50 MG
Supplier: Medchemexpress LLC HY13960950MG
Camonsertib is an orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM in biochemical assays. It demonstrates 30-fold selectivity for ATR over mTOR and over 2,000-fold selectivity over ATM, DNA-PK, and PI3Kα kinases, exhibiting potent antitumor activity.
- Orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM.
- Demonstrates 30-fold selectivity for ATR over mTOR.
- Exhibits potent antitumor activity.
- Inhibits CHK1(Ser345) phosphorylation in LoVo cells.
- Produces dose-dependent tumor growth inhibition in xenografts.
- Shows greater anti-tumor effects in combination with PARPi Olaparib.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?