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Eurofins Discoverx cAMP Hunter eXpress MC4R CHO-K1 GPCR Assay, 2-Plate Kit. (95-0050E2CP2M)
Supplier: Eurofins Discoverx 950050E2CP2M

The cAMP Hunter MC4R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. α-melanocyte stimulating hormone) based activation of MC4R GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type MC4R, a naturally Gs coupled GPCR. Upon activation of MC4R, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
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