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Invitrogen™ Canine IGFBP-2 ELISA Kit

Catalog No. EC9RBX5
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EC9RB 96 Tests
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ELISA

Canine IGFBP-2 quantitates canine IGFBP-2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant canine IGFBP-2.

IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number AI255832; BP2; BRL-BP; IBP2; IBP-2; IGF binding protein 2; IGF-binding protein 2; IGFBP; IGFBP2; Igfbp-2; IGF-BP53; ILGFBPA; Insulin like growth factor binding protein; insulin like growth factor binding protein 2; insulin-like growth factor binding protein 2; insulin-like growth factor binding protein 2, 36 kDa; insulin-like growth factor-binding protein 2; mIGFBP-2; OTTHUMP00000207753
Assay Range 0.055 to 12.50 ng/mL
Assay Sensitivity 0.055 ng/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 488516
Gene Symbol IGFBP2
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target IGFBP2
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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