Cantharidin, 98%, Thermo Scientific Chemicals

Description

 

Cantharidin is used as a potent inhibitor of PP2A phosphatase activity. It has been shown to stimulate cell cycle progression and induce premature mitosis, used topically (0.7%) as an anti-wart treatment, and has been shown to be active in cervical, tongue, neuroblastoma, bone, leukemia, ovarian, colon, and various other cancer cell lines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cantharidin is used as a potent inhibitor of PP2A phosphatase activity. It has been shown to stimulate cell cycle progression and induce premature mitosis, used topically (0.7%) as an anti-wart treatment, and has been shown to be ac

Specifications

Chemical Identifiers

• CAS: 56-25-7
• Molecular Formula: C10H12O4
• Molecular Weight (g/mol): 196.202
• MDL Number: MFCD00134968
• InChI Key: DHZBEENLJMYSHQ-XCVPVQRUSA-N
• Synonym: cantharidin, cantharone, cantharidine, kantaridin, kantharidin, cantharides camphor, kantharidin german, caswell no. 157, 1,2-dimethyl-3,6-epoxyperhydrophthalic anhydride, unii-igl471wq8p
• PubChem CID: 5944
• ChEBI: CHEBI:64213
• SMILES: CC12C3CCC(C1(C(=O)OC2=O)C)O3

• Melting Point: 215°C to 217°C
• Color: White
• Quantity: 100 mg
• UN Number: UN2811
• Merck Index: 14,1752
• Solubility Information: Soluble in DMSO (25mg/ml warm),acetone (8mg/ml),ethanol (8mg/ml warm),chloroform (1:65),ether (1:560),and ethyl acetate (1:150).
• Formula Weight: 196.2
• Percent Purity: 98%
• Physical Form: Powder
• Chemical Name or Material: Cantharidin

Safety and Handling

Hazard Category	H300-H315-H319-H335
Hazard Statement	GHS H Statement H300-H315-H319-H335 Fatal if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	200-263-3
RTECSNumber	RN8575000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only