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Selleck Chemical LLC Capmatinib (INCB28060) 10mg 1029712-80-8 INC280, NVP-INC280

Supplier: Selleck Chemical LLC S278810MG
Capmatinib (INCB28060, INC280, NVP-INC280) is a novel, ATP-competitive inhibitor of c-MET with IC50 of 0.13 nM in a cell-free assay, inactive against RON?, as well as EGFR and HER-3. Capmatinib (INCB28060) inhibits Wnt/?-catenin and EMT signaling pathways and induces apoptosis in diffuse gastric cancer positive for c-MET amplification. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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