Thermo Scientific™ CaptureSelect™ Bovine IgA Affinity Matrix

Description

Thermo Scientific™ CaptureSelect™ Bovine IgA Affinity Matrix has been designed specifically for the purification of bovine IgA from whey.

CaptureSelect Bovine IgA Affinity Matrix has been designed specifically for the purification of bovine IgA from whey.

Features of this affinity matrix include:

• Binds monomeric, dimeric, and secretory bovine IgA
• One-step purification from whey
• Excellent scalability

Free of animal components

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

Main characteristics:

• Matrix: agarose-based, aldehyde-activated
• Average particle size: 65 ± 10 μm
• Ligand: CaptureSelect Bovine IgA affinity ligand
• Ligand coupling method: aldehyde coupling via NH₂ residues of the ligand
• Binding capacity: ∼10 g/L resin
• Elution conditions: 0.1 M citric acid pH 3.0 or 0.1M glycine pH 3.0
• Flow characteristics: 50–200 cm/h (up to 2 bar)
• Formulation buffer: 20% (v/v) ethanol

Specifications

• Binding Capacity: ∼10 g/L resin
• Flow Rate: 50 to 200 cm/hr. (Up to 2 bar)
• Matrix: Agarose-based, aldehyde-activated
• Content And Storage: Store at 2°C to 8°C.
• Particle Size: 65 ±10 μm
• Form: Liquid Suspension
• Product Line: CaptureSelect™
• Quantity: 50 mL
• Type: Affinity Matrix
• Ligand Type: Bovine IgA affinity ligand
• Stationary Phase: Anti Bovine IgA