Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Protein Purification
  5. Protein Purification Reagents and Kits
  6. Thermo Scientific™ CaptureSelect™ IgA-XL Affinity Matrix

Thermo Scientific™ CaptureSelect™ IgA-XL Affinity Matrix

Catalog No. 2943972005
Click to view available options
Quantity:
5 mL

Description

Thermo Scientific™ CaptureSelect™ IgA-XL Affinity Matrix is intended for the purification of human IgA, with no binding to other immunoglobulins.

CaptureSelect IgA-XL Affinity Matrix is intended for the purification of human IgA, with no binding to other immunoglobulins. The IgA-XL affinity matrix provides improved binding capacities (>15 g/L IgA) and elution characteristics (full elution at pH 4) compared to CaptureSelect IgA Affinity Matrix.

Features of this affinity matrix include:

  • Purification of all IgA serotypes: IgA1, IgA2, dimeric IgA, and S-IgA (secretory IgA)
  • IgA purification from plasma, serum, and recombinant sources
  • Efficient purification of IgA with high yields and retained activity
  • Excellent scalability
  • Non-animal-derived

CaptureSelect IgA-XL Affinity Matrix binds to the Fc part of IgA. The high selectivity and yields obtained using IgA-XL Affinity Matrix enable a robust, fast, and efficient purification process with excellent purity obtained in one step.

Animal origin statement

CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12–15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (animal origin-free).

Main characteristics

  • Matrix: agarose-based, epoxide activated
  • Average particle size: 65 ± 10 μm
  • Ligand: CaptureSelect IgA-XL affinity ligand
  • Ligand coupling method: epoxide
  • Binding capacity: > 15 g/L at 5 minutes residence time, tested with plasma-derived polyclonal IgA
  • Elution conditions: 20 mM sodium citrate, pH 4
  • Flow characteristics: 50–200 cm/h (up to 2 bar)
  • Formulation buffer: 20% (v/v) ethanol

Specifications

Flow Rate 50–200 cm/hr. (up to 2 bar)
Formulation 20% (v/v) ethanol
Content And Storage Store at 2–8°C. Protect from direct sunlight.
Particle Size 65 ±10 μm
Form Resin Slurry
Product Line CaptureSelect™
Quantity 5 mL
For Use With (Application) Purification of all IgA subtypes (IgA1, IgA2, dimeric IgA, secretory IgA)
Target IgA-Fc domain
Type Affinity Matrix
Ligand Type CaptureSelect IgA-XL Affinity Ligand
Show More Show Less
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.