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Thermo Scientific™ CaptureSelect™ TSH Affinity Matrix
Description
CaptureSelect TSH Affinity Matrix was specifically designed for the purification of thyroid-stimulating hormone (TSH) from recombinant sources.
Some features of CaptureSelect TSH Affinity Matrix include:
- Highly selective for thyroid-stimulating hormone with no affinity for the other gonadotropins (FSH, LH, and HCG)
- Enables efficient purification of recombinant TSH with high yields and retained activity
- Offers excellent scalability
- Non–animal-derived
The high selectivity and yields obtained using CaptureSelect TSH Affinity Matrix enable a robust and efficient purification process with excellent purity obtained in one step.
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
Main characteristics:
- Matrix: agarose bead
- Average particle size: 65 μm
- Ligand: CaptureSelect TSH affinity ligand
- Ligand coupling method: epoxide
- Binding capacity: >5 mg/mL of resin
- Elution conditions: 0.1 M citrate buffer, pH 3.0
- Flow characteristics: 50–200 cm/h (up to 2 bar)
- Formulation buffer: 20% (v/v) ethanol
Specifications
Specifications
| Binding Capacity | >5 mg/mL |
| Flow Rate | 50 to 200 cm/hr. (Up to 2 bar) |
| Matrix | Agarose-based |
| Content And Storage | Store at 2°C to 8°C. |
| Shipping Condition | Qualified for Ambient or Wet Ice |
| Particle Size | 65 μm |
| Form | Agarose Bead |
| Product Line | CaptureSelect™ |
| Quantity | 50 mL |
| Target | Thyroid-Stimulating Hormone (TSH) |
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