Carbachol, 98.3%

Description

Carbachol, CAS # 51-83-2, is a parasympathomimetic that acts on acetylcholine receptors. | CAS: 51-83-2 | C6H15ClN2O2 | 182.65 g/mol

Carbachol is a cholinergic agonist and is used for the treatment of glaucoma. It is also used as ophthalmic solution (eye drops) during ophthalmic surgery.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Carbachol is an ammonium salt and a choline ester that acts on both muscarinic and nicotinic receptors
• Carbachol activates the sympathetic nervous system; it leads to intracellular increases in Ca2+ and activates associated signaling pathways
• Carbachol is not degraded by the cholinesterases

Application

• Carbachol can inhibit apoptotic cell death, making it useful for the study of cell survival and growth in laboratory settings
• Carbachol can be used for laboratory research of any biological pathway that depends on acetylcholine, including sleep cycles and motor control

Specifications

Chemical Identifiers

• CAS: 51-83-2
• Molecular Formula: C6H15ClN2O2
• Molecular Weight (g/mol): 182.65
• MDL Number: MFCD00012011
• InChI Key: AIXAANGOTKPUOY-UHFFFAOYSA-N
• Synonym: carbachol, carbamoylcholine chloride, carbachol chloride, carbacholine, carbocholine, jestryl, doryl, carbamylcholine chloride, miostat, isopto carbachol
• PubChem CID: 5831
• ChEBI: CHEBI:3385
• IUPAC Name: 2-(trimethylazaniumyl)ethyl carbamate chloride
• SMILES: [Cl-].C[N+](C)(C)CCOC(N)=O

• Melting Point: ∽210°C (decomposition)
• Quantity: 1 g
• UN Number: UN2811
• Beilstein: 3917459
• Sensitivity: Hygroscopic
• Merck Index: 14,1779
• Solubility Information: Soluble in water and dimethyl sulfoxide.
• Formula Weight: 182.65
• Percent Purity: 98.3%
• Chemical Name or Material: Carbachol

Safety and Handling

Hazard Category	H300-H500
Hazard Statement	GHS H Statement H300 Fatal if swallowed.
Precautionary Statement	P264b-P270-P301+P310-P330-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	200-127-3
RTECSNumber	GA0875000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only