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Cayman Chemical CarbaethopendecInbromIde 100mg
Supplier: Cayman Chemical 37482100 MG
An indole with diverse biological activities selectively inhibits BChE (IC50s 1.97 and 4.97 UM for the human and horse enzymes respectively) over AChE for which it has no activity an inhibitor of 5-HT3A and 5-HT3AB (IC50s 65.35 and 28.44 UM respectively) reduces glutamate-induced increases in cell death in HT22 cells at 50 and 100 UM induces apoptosis in A549 and H1299 NSCLC cells at 40 60 and 80 UM reduces tumor growth and intratumoral levels of phosphorylated GSK3B in an A549 mouse xenograft model at 10 mg/kg also reduces infarct size and cardiac cell apoptosis and prevents cardiac dysfunction in a rat model of ischemia-reperfusion injury at 20 mg/kg
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