Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Cayman Chemical CarbamazepIn 5g
Supplier: Cayman Chemical 154225 G
A sodium channel inhibitor; preferentially inhibits inactivated Nav1.7 and Nav1.3 channels (IC50s = 406 and 900 µM, respectively) over resting (closed) Nav1.7 and Nav1.3 channels in whole-cell patch-clamp assays using HEK293 cells (IC50s = 1,584 and 2,464 µM, respectively); inhibits sodium currents in a rat sciatic nerve patch-clamp assay ex vivo at 100 µM; reduces dopamine levels in the striatum and hippocampus, as well as L-DOPA levels in the striatum, in rats at 100 mg/kg; reduces amphetamine-induced hyperactivity in mice at 0.5% w/w in the diet; reduces immobility time in the forced swim test in mice at 0.75% w/w in the diet
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?