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Apexbio Technology LLC Carbenoxolone disodium 7421-40-1 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A83895.1
Carbenoxolone disodium (CAS 7421-40-1) is a small-molecule inhibitor targeting 11 -hydroxysteroid dehydrogenase (11 -HSD) It is designed to modulate glucocorticoid metabolism by suppressing the interconversion of corticosteroid hormones thereby regulating glucocorticoid access to steroid receptors Carbenoxolone disodium exerts its biological activity through inhibition of 11 -HSD enzymatic function In vitro studies demonstrate inhibitory activity with reported IC50 values ranging from 10 30 M depending on experimental conditions and target tissue Based on these pharmacological properties Carbenoxolone disodium holds research potential in neuroendocrine and cardiovascular studies exploring glucocorticoid-mediated signaling pathways
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