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Cayman Chemical CarbetocInacetate 50mg

Supplier: Cayman Chemical 3323450 MG

A prodrug form of GS-443902 reduces viral titers in primary HAE cells infected with MERS-CoV or SARS-CoV (EC50s 0.074 and 0.069 UM respectively) reduces infectious virus production in SARS-CoV-2-infected HAE cells (EC50 10 nM) reduces lung viral titers and prevents weight loss in a mouse model of SARS-CoV infection at 25 and 50 mg/kg reduces lung viral titer and lung hemorrhage and improves pulmonary function in mice infected with a chimeric SARS-CoV encoding the SARS-CoV-2 RdRp at 25 mg/kg
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