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Medchemexpress LLC Carboxy-PTIO potassium | 148819-94-7 | 99.0% | 315.39 | 50 MG
Supplier: Medchemexpress LLC HY18734A50MG
Carboxy-PTIO potassium is a potent nitric oxide (NO) scavenger that rapidly reacts with NO to produce NO2. It can prevent hypotension and endotoxic shock through its direct NO-scavenging action in a lipopolysaccharide-stimulated rat model. This compound is intended for research use only and is not sold to patients.
- Potent nitric oxide (NO) scavenger
- Reacts quickly with NO to produce NO2
- Can prevent hypotension and endotoxic shock by scavenging NO in LPS-stimulated rat models
- Significantly suppresses stimulation of NO expression induced by Physalin A treatment in vitro
- Reduces Physalin A-induced cleavage of procaspase-3 and PARP, and down-regulates ICAD expression, diminishing DNA fragmentation in nuclei
- Reverses decreased mTOR and p-mTOR levels induced by Physalin A, with concomitant suppression of LC3 I to LC3 II conversions in A375-S2 cells
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