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Medchemexpress LLC Carboxy pyridostatin trifluoroacetate salt | 2444713-88-4 | 99.5% | 820.73 | 100 MG
Supplier: Medchemexpress LLC HY112680A100MG
Carboxy pyridostatin trifluoroacetate salt is a G-quadruplex ligand with high molecular specificity to RNA on DNA G4s, and it also reduces ATF-5 protein. This compound is known to decrease cell proliferation and inhibit stress granule (SG) formation. It is intended for research use only.
- Reduces the size of adult SVZ-derived neurospheres and the number of cells in neurospheres.
- Blocks proliferation and neurosphere fusion in adult SVZ-derived neurosphere cultures.
- Hinders stress granule (SG) formation in U2OS cells.
- Significantly reduces the number of PCNA-expressing cells in the adult SVZ.
- Increases the number of OLIG2-expressing cells in the corpus callosum in C57BL/6 mice.
- Affects the differentiation of neural stem and progenitor cells in different brain regions.
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