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Medchemexpress LLC Cariprazine hydrochloride | 1083076-69-0 | 99.9% | 463.87 | 100 MG
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Supplier:  Medchemexpress LLC HY14763A100MG

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Cariprazine hydrochloride is a novel antipsychotic agent candidate with high affinity for D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).

  • Demonstrates high potency in stimulating inositol phosphate (IP) formation.
  • Exhibits approximately 10-fold higher affinity for human D3 versus human D2L and D2S receptors.
  • Displays high affinity and pure antagonism at human serotonin (5-HT) type 2B receptors.
  • More potent than Aripiprazole in inhibiting isoproterenol-induced cAMP production in HEK-293 cells.
  • Achieves dose-dependent dopamine D2/D3 receptor occupancy.
  • Significantly reduces ouabain-induced hyperactivity.

Catalog No. 50-003-60085


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