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AdipoGen CARMA1 pAb AL220

Supplier: AdipoGen AG25B0004VC100
Polyclonal Antibody. Recognizes human and mouse CARMA1. Detects a band of ~130Dka by Western blot. Source Rabbit. Applications ICC, IHC, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. CARMA1 is involved in the costimulatory signal essential for T cell receptor TCR-mediated T cell activation. Its binding to DPP4 induces T cell proliferation and NF-kappaB activation in a T cell receptor/CD3-dependent manner. CARMA1 activates NF-kappaB via Bcl10 and IKK.
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