Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 501639239

Medchemexpress LLC Carmofur (HCFU) | 61422-45-5 | 99.9% | 500 MG
SDP

Supplier:  Medchemexpress LLC HYB0182500MG

Encompass_Preferred

Carmofur (HCFU) is a rat recombinant acid ceramidase inhibitor with an IC50 of 29 nM. It also functions as a protease inhibitor of SARS-CoV-2 main protease (Mpro), fatty acid amide hydrolase (FAAH), and N-acylethanolamine acid amidase (NAAA). This compound demonstrates anti-cancer, anti-inflammatory, and anti-virus activities, making it valuable for research into COVID-19 and acute lung injury (ALI).

  • Inhibits acid ceramidase (AC) activity in human colon cancer SW403 cells.
  • Inhibits SARS-CoV-2 activity in Vero E6 cells.
  • Acts as an inhibitor of FAAH and NAAA activities in HEK293 cells.
  • Shows anti-inflammatory effects in Raw264.7 cells by reducing pro-inflammatory cytokines.
  • Improves LPS-induced inflammatory responses and promotes resolution of lung injury in acute lung injury (ALI) mice models.
  • Inhibits AC activity in various tissues in male Swiss Webster mice.

Catalog No. 50-163-9239


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.