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Medchemexpress LLC (±)-Carnitine chloride | 461-05-2 | 98.0% | 1 ML
Supplier: Medchemexpress LLC HYB145310MM/1ML
(±)-Carnitine chloride, also known as DL-Carnitine chloride, is a compound with both D and L isomers. L-carnitine plays a vital role in the β-oxidation of fatty acids and exhibits significant antioxidant and anti-inflammatory activities, making it valuable for various biological studies.
- Facilitates shuttling of long-chain fatty acids across the inner mitochondrial membrane.
- Increases palmitoyl-CoA-induced mitochondrial respiration.
- Augments Nrf2 nuclear translocation and HO-1 expression.
- Protects cells against H2O2-induced cell damage via Akt-mediated Nrf2 signaling.
- Down-regulates ubiquitin proteasome pathway and increases IGF-1.
- Alleviates skeletal muscle atrophy in animal models.
- Suppresses atrogin-1 mRNA expression.
- Reduces renal fibrosis and pro-oxidative and proinflammatory states.
- Increases PPAR-γ expression.
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