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Apexbio Technology LLC Carteolol HCl 51781-21-6 100mg
Supplier: Apexbio Technology LLC B5944100
Carteolol hydrochloride (CAS 51781-21-6) is a non-selective -adrenergic receptor antagonist with partial agonist properties In vitro studies demonstrate that carteolol interacts with 1-adrenergic receptors exhibiting agonist activity at low-affinity (Propranolol-insensitive) sites and antagonistic effects at high-affinity sites In vivo carteolol and its metabolite 8-hydroxy carteolol reduce experimentally induced intraocular pressure (IOP) in animal models with the metabolite showing enhanced efficacy Carteolol is widely utilized in research relating to cardiovascular diseases and ocular hypertension including the modeling of chronic glaucoma and -adrenergic signaling pathways
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