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Cayman Chemical Cas9 mRNACap-1mo5U 100ug

Supplier: Cayman Chemical 41964100 UG

An antiviral ribonucleoside analog incorporation of EIDD-2749 into RSV or SARS-CoV-2 RNA inhibits viral RdRp and induces transcriptional stalling in cell-free assays reduces viral yield in HEp-2 cells infected with clinical isolates of RSV (EC50s 0.61-1.2 UM) reduces apical virus shedding in RSV-infected isolated HAE cells (EC50 55 nM) reduces lung virus load in a mouse model of RSV infection at 5 mg/kg reduces nasal viral titers in a ferret model of SARS-CoV-2 infection at 15 and 50 mg/kg
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