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Medchemexpress LLC Casopitant mesylate | 414910-30-8 | 99.8% | C31H39F7N4O5S | 1 ML
SDP

Catalog No. 5000353889
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Casopitant mesylate is a potent, selective, brain-permeable, and orally active neurokinin 1 (NK1) receptor antagonist. It functions as a second-in-class antiemetic by antagonizing the emetogenic effect of Substance P. This compound also acts as a substrate and a weak-to-moderate inhibitor of CYP3A4, making it suitable for addressing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV).

  • Potent, selective, brain-permeable, and orally active
  • Functions as a neurokinin 1 (NK1) receptor antagonist
  • Antagonizes the emetogenic effect of substance P
  • Substrate and weak-to-moderate inhibitor of CYP3A4
  • Used for chemotherapy-induced nausea and vomiting (CINV)
  • Used for postoperative nausea and vomiting (PONV)

Catalog No. 50-003-53889 Supplier Medchemexpress LLC Supplier No. HY14405A10MM/1ML
May include imposed supplier surcharges.
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Casopitant mesylate is a potent, selective, brain-permeable, and orally active neurokinin 1 (NK1) receptor antagonist. It functions as a second-in-class antiemetic by antagonizing the emetogenic effect of Substance P. This compound also acts as a substrate and a weak-to-moderate inhibitor of CYP3A4, making it suitable for addressing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV).

  • Potent, selective, brain-permeable, and orally active
  • Functions as a neurokinin 1 (NK1) receptor antagonist
  • Antagonizes the emetogenic effect of substance P
  • Substrate and weak-to-moderate inhibitor of CYP3A4
  • Used for chemotherapy-induced nausea and vomiting (CINV)
  • Used for postoperative nausea and vomiting (PONV)

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