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Apexbio Technology LLC Caspase-3 Fluorometric Assay Kit,25 assays
Supplier: Apexbio Technology LLC K200725
Cysteine-dependent aspartate-directed proteases (Caspases) are a family of cysteine proteases that play important roles in apoptosis, necrosis, and inflammation. Sequential activation of caspases plays an important role in cell apoptosis. Caspase-3 is a caspase protein that cleaves and activates caspases 6 and 7, and is processed and activated by caspases 8, 9, and 10. Caspase-3 is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with Alzheimer's disease. Caspase-3 recognizes tetra-peptide sequences D-x-x-D and hydrolyzes peptide bonds after aspartic acid residues. Other sizes are also available. Please inqury us for quote.
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