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Diagnostic Biosystems CASPASE 1 Caspase 1/Interleukin-1-β Converting Enzyme
Supplier: Diagnostic Biosystems PDR175
Caspase 1 and is expressed as a proenzyme in many tissues. Active Caspase 1 is a tetramer of two subunits p10 and p20 in 2:2 ratio. Overexpression of caspase 1 can induce apoptosis in fibroblast, which can be inhibited by overexpression of Crm A, a protein from pox virus.
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