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CPC Scientific MCA-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OH 0.5MG
Supplier: CPC Scientific CASP027A
Highly fluorescent substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of this substrate at position P1 Asp causes continuous fluorescent assay monitored at an emission wavelength of 393 nM. Furthermore, caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis.SEQUENCE: MCA-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OHONE-LETTER SEQUENCE: Mca-YVADAP-Lys(DNP)MOLECULAR FORMULA: C53H64N10O19MOLECULAR WEIGHT: 1145.15STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [189696-01-3]SYNONYMS: Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OHRESEARCH AREA: ApoptosisREFERENCES:M. Enari et al., Nature, 380, 723 (1996)SKU(s): CASP-027A, CASP-027B, CASP-027C
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