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CPC Scientific Ac-Leu-Glu-His-Asp-pNA (trifluoroacetate salt) 1MG
Supplier: CPC Scientific CASP091B
pNA (4-nitroaniline)-derived caspase substrates widely used for various caspase activities and colorimetric detection. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm. Caspase-9 substrate. ONE-LETTER SEQUENCE: Ac-LEHD-pNAMOLECULAR FORMULA: C29H38N8O11MOLECULAR WEIGHT:674.7STORAGE CONDITIONS: -20 5CRESEARCH AREA: ApoptosisREFERENCES: Grutter MG (2000) Curr Opin Struct Biol 10, 649-55; Gastman BR (2001) Head Neck 23, 409-25; Grutter MG (2000) Curr Opin Struct Biol 10, 649-55; Stennicke HR and Salvesen GS (1999)Cell Death Differ 6, 1054-9; Stennicke HR and Salvesen GS (1998) Biochim Biophys Acta 1387, 17-31; Thornberry NA and Lazebnik Y (1998) Science 281, 1312-6; Talanian RV, et al. (1997) . J Biol Chem 272, 9677-82.; Fassy F, et al. (1998) Eur J Biochem 253, 76-83, Datta R, et al. (1996) Blood 88, 1936-43; Koeplinger KA, et al. (2000) Protein Expr Purif 18, 378-87
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