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Apexbio Technology LLC Caspofungin(Synonyms: Cancidas, Caspofungin acetate, MK-0991, L-743872), 10mM (in 1mL DMSO), CAS: 162808-62-0.
Supplier: Apexbio Technology LLC B49725.1
Caspofungin (CAS 162808-62-0) is a small-molecule inhibitor of -1 3-glucan synthase an enzyme essential for the biosynthesis of -(1 3)-D-glucan a fundamental cell wall component in pathogenic fungi such as Candida albicans Caspofungin selectively inhibits -1 3-glucan synthase activity with a reported IC50 of approximately 0 6 nmol/L in membrane preparations of C albicans Caspofungin demonstrates potent antifungal activity against various Candida isolates including azole-resistant strains (MIC90 0 5 g/mL) and shows prolonged post-antifungal effects lasting 6 8 hours It is widely utilized in biomedical research involving fungal infections and antifungal therapeutics
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