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Medchemexpress LLC Catechin | 154-23-4 | 290.27 | 100 MG
Supplier: Medchemexpress LLC HYN0898100MG
Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
- Mechanism of action: inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM and exhibits >95% inhibitory activity at 70 μg/mL against COX-1.
- Cellular effects: induces apoptosis in MCF-7 cells in a dose- and time-dependent manner, leading to increased expression levels of Caspase-3, -8, -9, and p53.
- In vivo effects: prevents time-induced episodic memory deficits in animals in a dose-dependent manner (most effective at 200 mg/kg, p.o.) and prevents the rise in MPO level.
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