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AdipoGen Catechin
Supplier: AdipoGen CDXC0453M005
Chemical. CAS 18829-70-4. Formula C15H14O6. MW 290.27. Catechins have wide biological functionality, including antioxidant, anti-inflammatory, antiviral and anticancer activities. Catechins also play a key role in regulating carbohydrate and lipid metabolism. --Catechin is comparatively less bioavailable than the stereoisomer -catechin for intestinal absorption. It shows antioxidant free radical scavenging and antidiabetic activities. --Catechin has been shown to be a stereoselective PPARgamma agonist. It activates PPARgamma in a dose-dependent fashion, promotes adipocyte differentiation and increases sensitivity to insulin. It markedly suppresses the expression of Kruppel-like factor 7 KLF7 protein, which has recently been reported to inhibit the expression of adiponectin and other adipogenesis related genes, including leptin, PPARgamma, C/EBPalpha, and aP2 in adipocytes. It also has shown to have anti-reverse transcriptase activity and maltase inhibitory activity.
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