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Biotium Catenin, alpha-1 (CTNNA1) (1G5), CF405S conjugate, 0.1mg/mL
Supplier: Biotium BNC041364100
Alpha-E-catenin (also known as Alpha-1 catenin) is part of the catenin family, a large family of Ca2 -dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-E-catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, alpha-E-catenin forms a heterodimer with beta-catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-E-catenin also regulates the beta-catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can g
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