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Cayman Chemical Catenin PhosphoSer33 37 Pol
Supplier: Cayman Chemical 100091801 EA
Antigen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser33,37 of human β-catenin · Host: rabbit · Cross-reactivity: (+) human β-catenin · Application: WB • β-Catenin is a central component of the cadherin cell adhesion complex and plays an essential role in neural development in the Wingless/Wnt signaling pathway. It is thought to be regulated by the sequential phosphorylation of Ser29, Ser33, Ser37, and Thr41 by GSK3β. This hyperphosphorylation promotes the ubiquitylation and targeted destruction of β-catenin.
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