Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Cayman Chemical CathepsIn G InhIbItr I 1mg
Supplier: Cayman Chemical 149281 MG
A cathepsin G inhibitor (IC50 = 53 nM); selective for cathepsin G over thrombin, Factor Xa, Factor IXa, plasmin, trypsin, and PR3 (IC50s = >100 µM for all), but also weakly inhibits chymotrypsin; inhibits cathepsin G-induced activation of IL-36 in neutrophil degranulates at 10 µM; reduces CD4+ T cell-induced secretion of IFN-γ and IL-17 in B cells incubated with TTC and also reduces TTC presentation in B cells at 10 µM; decreases the size of neuromyelitis optica lesions and reduces the number of perivascular neutrophils when used in combination with sivelestat in a mouse model of IgG-induced brain injury at 5 UG/animal
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?