Medchemexpress LLC CAY 10465 | 688348-33-6 | 98.3% | 317.13 | 100 MG

Supplier:  Medchemexpress LLC HY112627100MG

CAY 10465 is a selective and high-affinity Aryl Hydrocarbon Receptor (AhR) agonist, with a Ki of 0.2 nM. It demonstrates no effect on the estrogen receptor (Ki >100000 nM). In vitro, CAY 10465 (at concentrations from 0.01 nM to 100 μM) has been shown to reduce apolipoprotein A-I (apo A-I) levels in HepG2 cells and inhibit the synthesis of this protein.

• Selective AhR agonist: High affinity for AhR with a Ki of 0.2 nM.
• No estrogen receptor effect: Shows no activity on the estrogen receptor (Ki >100000 nM).
• Inhibits apolipoprotein A-I: Reduces apo A-I levels and inhibits its synthesis in HepG2 cells.
• Appearance: Solid, white to off-white.
• Storage:
  Powder: -20°C for 3 years, 4°C for 2 years.
  In solvent: -80°C for 2 years, -20°C for 1 year.

Catalog No. 50-004-37567