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Cayman Chemical CAY10499 Fatty Acids and Deriv
Supplier: Cayman Chemical 100078751 MG
A non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively); inhibits ATGL, DAGLa, ABHD6, and CES1 at 5 mM; inhibits the growth of MCF-7, MDA-MB-231, COV318, and OVCAR-3 cancer cells (IC50s = 4.2, 46, 106.7, and 79.8 µM, respectively); reduces FRUC diet- and AIN-93M diet-induced increases in cytosolic lipase activity in rats
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