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Medchemexpress LLC CB-6644 5mg | 2316817-88-4 | 5 MG
Supplier: Medchemexpress LLC HY1144295MG
CB-6644 is a selective allosteric inhibitor of the RUVBL1/2 ATPase with a reported IC50 of 15 nM. It exhibits antiproliferative activity in multiple cancer cell lines and oral antitumor efficacy in xenograft models.
- Selective inhibitor of the RUVBL1/2 complex
- Blocks ATPase activity with an IC50 of 15 nM
- Demonstrates antiproliferative activity in vitro
- Shows oral antitumor efficacy in xenograft models
- Solid, white to light yellow appearance
- Soluble in DMSO (100 mg/mL); in vivo formulations reported at ≥ 2.08 mg/mL
- Store solid at -20°C under nitrogen; solutions at -80°C for long-term storage
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