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Medchemexpress LLC CB096 | 108883-90-5 | 98.7% | 285.25 g·mol⁻¹ | C14H11N3O4 | 250 MG
Supplier: Medchemexpress LLC HYW141374250MG
CB096 is a small-molecule RNA translation inhibitor that binds the 5′CGG/3′GGC internal loop of r(G4C2)exp RNA, disrupting its gain-of-function mechanism and reducing production of toxic dipeptide repeats. It inhibits RAN translation in cell assays (IC50 = 20 μM in HEK293T) and modulates RNA splicing and nucleocytoplasmic transport.
- Inhibits RAN translation in cells (IC50 = 20 μM in HEK293T).
- Binds the 5′CGG/3′GGC internal loop of r(G4C2)exp RNA.
- High purity of 98.72%.
- Solid, yellow to orange appearance.
- Soluble in DMSO at 50 mg/mL.
- Storage: sealed, away from moisture; in solvent -80°C (6 months) or -20°C (1 month).
- Available in multiple quantities for research use.
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